Furosemide

Furosemide Tablets are a potent 'loop' diuretic used in the treatment of oedema resulting from cardiac insufficiency, hepatic or renal dysfunction, parasitism, or of a traumatic origin. They are most commonly used as part of the medical management of congestive heart failure and other conditions where the body is retaining too much fluid.

Furosemide Tablets are flat faced, white circular tablets with bevelled edges. They are scored with a half break line for accurate dosing.

£0.08

Furosemide Tablets 20mg are indicated for the treatment of oedema associated with cardiac insufficiency, renal dysfunction, and trauma in cats and dogs. Furosemide is the most commonly used...

Furosemide Tablets 40mg are indicated for the treatment of oedema associated with cardiac insufficiency, renal dysfunction, and trauma in cats and dogs.

Contra-indicationsDo not use in acute glomerular nephritis, in electrolyte diseases, in patients with anuria, or patients that have received excessive doses of cardiac glycosides. Because of the danger of potentiating their toxic effects do not use with aminoglycoside or cephalosporin antibiotics. Allergic reactions have been associated with use with sulphonamides.

Special WarningsThe patient may increase its water intake to compensate for the diuresis. Consideration should be given to restricting water intake if the patient's condition makes such a course appropriate.

Special PrecautionsSpecial precautions for use in animals:Prolonged dosage may on occasions justify potassium supplementation and thus monitoring for hypokalaemia should be considered, especially if the product is used in conjunction with cardiac glycosides.Special precautions to be taken by the person administering the medicinal product to animals:Wear gloves or wash hands immediately after handling tablets. In case of accidental ingestion seek medical attention and show product label and/or pack insert to the doctor.

Adverse ReactionsNone reported

Pregnancy and LactationThe safety of use in pregnancy is not well established and a careful assessment of the likely benefits and potential risks should be made. A deleterious effect on lactation is to be expected, particularly if drinking water is restricted. Furosemide passes into milk, but not to a great extent.

InteractionsPotential interactions with other drugs include ototoxicity with aminoglycosides and nephrotoxicity with cephalosporins. Use in combination with sulphonamide treatment may lead to sulphonamide allergy. There is a possibility of interaction with cardiac glycosides.

Amounts to be Administered and Administration Route5mg/KgBW, one or two times per day. For patients weighing less than 8Kg dosage with the 20mg tablet (which may be halved) is recommended. Avoid overdosage in weak and old patients.

OverdoseDehydration and electrolyte depletion may occur. Monitor and correct, as necessary. Dosage higher than that which is recommended, may cause transitory deafness. Cardiovascular side effects may be observed in weak and old patients following overdose.

Withdrawal PeriodsNone for these species.

Forincible{" exposures"":".

Furosemide (Lasix), the medication that treats fluid retention in dogs, has been a cornerstone in the treatment of congestive heart failure (CHF). The drug is available in various strengths, including 40 mg, 40 mg, and 80 mg. Furosemide is a diuretic, which means it helps the body remove excess fluid. It works by increasing the amount of urine produced by the kidneys, helping to lower blood pressure and prevent further damage. While furosemide is effective for treating CHF, it is not the only option available. In cats, other alternatives may be necessary for the best outcomes.

Furosemide is a loop diuretic that works by increasing the amount of urine produced by the kidneys. It works by inhibiting sodium and chloride reabsorption in the ascending limb of the loop of Henle in the kidneys. This leads to an increase in the excretion of water, electrolytes, and other electrolytes from the blood and kidneys. It is a convenient option for many pet owners, especially for those with specific medical concerns. However, it is important to remember that the drug should only be used under the guidance of a veterinarian. Always consult with a veterinarian before administering furosemide to ensure proper dosage and duration.

Benefits of Furosemide (Lasix)

• Furosemide is an effective treatment for congestive heart failure and is widely used in veterinary medicine.
• Furosemide can be used to treat acute congestive heart failure in dogs, providing relief and supporting the dogs’ recovery.
• It is an excellent option for cats and dogs with a history of kidney disease, as it can be given in conjunction with other medications to prevent potential kidney damage.
• It is a safe and effective treatment for cats and dogs with frequent urination and vomiting.
• In clinical studies, furosemide reduced the rate of kidney damage in patients receiving high doses of furosemide, and improved survival rates in those patients.
• Furosemide is a widely prescribed medication for cats and dogs with congestive heart failure and is effective for its use in the treatment of acute congestive heart failure.

Benefits of Lasix (furosemide)

• Furosemide is a potent diuretic that helps to remove excess fluid from the body, making it a reliable option for cats and dogs with heart failure.
• Furosemide is safe and effective in cats and dogs with heart failure, with a long half-life of 4 to 6 hours.
• In veterinary medicine, furosemide is used to treat congestive heart failure and can help manage congestive heart failure in cats and dogs with congestive heart failure.
• In cats and dogs with heart failure, furosemide is a valuable medication for managing acute congestive heart failure.
• Furosemide is a potent diuretic, effective in managing congestive heart failure in cats and dogs with heart failure.

Recommended Dosage

• Furosemide should be given as a once-daily dose and administered as directed by a veterinarian.
• Dosage for cats and dogs with heart failure should be prescribed by a veterinarian based on the condition and the veterinarian’s medical history.
• Furosemide is generally safe, but for cats and dogs with heart failure, the dose should be adjusted based on individual clinical needs.
• Furosemide should not be given to pregnant or nursing animals.

Furosemide Dosage in Cats

• The dosage of furosemide for cats and dogs with heart failure should be determined by the veterinarian and the condition being treated.
• In clinical studies, furosemide given to cats and dogs with heart failure provided effective and sustained relief of acute congestive heart failure.
• The dosage for cats and dogs with heart failure should be determined by the veterinarian and the condition being treated.
• In cats and dogs with congestive heart failure, furosemide should be used with caution, especially in situations when other treatment options have failed.

Furosemide belongs to a group of medicines called diuretics (which increase the production of urine) and is used to treat high blood pressure, heart failure, and oedema (a build-up of fluid in the body). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. The higher this blood pressure, the harder the heart has to pump. As a result, it leads to heart disease, irregular heartbeat, and other complications. Oedema may occur in cases of high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to swelling.

Furosemide works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Your doctor will advise your dose and how often you need to take this medication based on your medical condition. In some cases, you may experience dehydration, headache, nausea, or dizziness. Most of these side effects of Furosemide do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take it if you are allergic to furosemide or any other components present in Furosemide. Try not to stop taking Furosemide of your own. Let your doctor know about this, as it may cause a rise in blood pressure and can increase the risk of getting heart disease and stroke. Inform your doctor if you are suffering from any kidney or liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Furosemide can be prescribed accordingly. The most common adverse effect of furosemide is having to pee more frequently than usual. To minimise needing to get out of bed to pee, avoid taking this medication within 4 hours of going to bed.

Your doctor will decide how much this medication your needs are willing to take based on your medical condition

Taking this medication may increase the risk of getting heart disease. If you are suffering from a diabetes or high blood pressure, then Furosemide may increase the risk of getting heart disease too. Tell your doctor if you are suffering from any eye diseases or if you have ever had any eye problems. Your doctor will determine whether Furosemide is right for you.

Taking Furosemide while you are pregnant or breastfeeding

If you are taking this medication during pregnancy or breastfeeding, tell your doctor. Taking this medication while you are pregnant or breastfeeding will not affect your ability to get or keep an erection. Taking this medication while you are breast feeding will not affect your ability to get an erection or your ability to get an erection during sex. However, you should avoid the use of alcohol while taking this medication and for at least 4 weeks after you stop taking it.

Tell your doctor if you are pregnant or intend to become pregnant. They will determine your safety and the necessity for this medication.

The use of Furosemide while you are pregnant or while breastfeeding

If you are taking this medication while you are pregnant or planning to become pregnant, tell your doctor. They will advise you when you may require an alternative treatment such as a vasectomy or vasectomy in order to get the benefits of this medication. Furosemide has been shown to benefit you in some cases and in others, it may affect your ability to get an erection. Your doctor will discuss with you whether Furosemide is the best choice for you for this treatment and whether alternative treatments are necessary.

It is not known if this medication is more effective in treating your condition or whether it may have a similar effect on your body. You should not take this medication if you are taking other diuretics such as aliskiren or furosemide. Furthermore, it should not be used by people who are hypersensitive (allergic) to any of the other ingredients of this medication. Furthermore, you should avoid taking any medicines while taking this medication and for at least 4 weeks after you stop taking it.

The use of Furosemide while you are lactating or taking a blood pressure medicine

If you are taking this medication while you are breastfeeding, your doctor will discuss with you the necessity for an alternative treatment such as a vasectomy or vasectomy in order to get the benefits of this medication. This treatment may cause a rise in blood pressure and a fall in your blood pressure may occur.

References

1. KD. Tripathi. Diuretics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 579-581.

2. Robert F. Reilley and Edwin K. Jackson. Regulation of renal function and vascular volume. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 682-686.

3. University of Pennsylvania. Furosemide for Accelerated Recovery of Blood Pressure Postpartum (ForBP). NIH U. S. National Library of Medicine ClinicalTrials.gov. [Revised in September 2020] [Accessed on 12th February 2021]

4. Nrebja and Montse. Randomized, open-label, blinded-endpoint study of furosemide for attenuated shortness of breath by the inhibition of vasoconstriction. Circ Int 2003 966 (PJM-18). eJ Acad Pharmacol 2014;40(9):1743-9.

5. Can you tell us we’ve never looked into the safety and effectiveness of furosemide for attenuated shortness of breath? [Revised in September 2020]

6. AIs.hitting the side effects section is – and should be – a habit-forming way to avoid having to stop smoking. See the end of this statement for more information.

7. Randomised, open-label, blinded-endpoint study of furosemide for attenuated shortness of breath.

8. Gomolak and Rückl. Randomized, open-label, blinded-endpoint study of furosemide for attenuated shortness of breath. Curr Opin Drug Metab Clin Pharmacol Ins 9 (suppl 1): 100.

9.

10.

11.

12. Khedez-Slinger and Düney. Curr Res Int Manuemate 84(5): 629–36.

13. U. Food and Drug Administration. The endocannabinoid system (ECS).

14. NIH. Norepinephrine and dopamine reuptake. [Approved in 2021]

15.

16.

17. Dopamine and norepinephrine reuptake.

18.

19.

20.